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CESAM chamber is a powerful infrastructure to investigate aerosol optical properties. It is equipped with in situ long path spectrometers to measure the aerosol extinction from UV-vis to mid-IR spectral ranges, and with various on-line techniques including nephelometer, aethalometer (7 wavelengths), CRDS. Different injection systems allow the introduction/generation of organic aerosol, soot, dust and salt. 

CESAM chamber can be combined with the POLLURISK platform to expose living organisms to atmospheric pollutants (controlled mixtures). The key features of CESAM-POLLURISK are:

• Exposure of preclinical models to urban atmospheric pollution 

• Biological facility to conduct analysis on preclinical models (as an illustration lung function, systemic response, biological analyses, blood/urine/organs sampling, …

• Exposure of preclinical models to more complex exposome as noise and stress

• Measurement of associated Oxidative Potential of the simulated exposome

  • Exposure of cells/organoids in parallel to in vivo studies (starting 2025): in a nutshell, in vivo studies are dedicated to establish the links between Exposome components and Health Effects, when in vitro studies will contribute to identify the nature of these links.